Doctor,
Explain GERD and LPR
What is GERD?
Gastroesophageal reflux, often referred to as GERD, occurs
when acid from the stomach backs up into the esophagus. Normally,
food travels from the mouth, down through the esophagus and into
the stomach. A ring of muscle at the bottom of the esophagus,
the lower esophageal sphincter (LES), contracts to keep the acidic
contents of the stomach from “refluxing” or coming back up into
the esophagus. In those who have GERD, the LES does not close
properly, allowing acid to move up the esophagus.
When stomach acid touches
the sensitive tissue lining the esophagus and throat, it causes
a reaction similar to squirting lemon juice in your eye. This
is why GERD is often characterized by the burning sensation known
as heartburn.
In some cases, reflux
can be SILENT, with no symptoms until a problem arises. Almost
all individuals have experienced reflux (GER), but the disease
(GERD) occurs when reflux happens on a frequent basis often over
a long period of time.
What is LPR?
During gastroesophageal
reflux, the acidic stomach contents may reflux all the way up
the esophagus, beyond the upper esophageal sphincter (a ring of
muscle at the top of the esophagus), and into the back of the
throat and possibly the back of the nasal airway. This is known
as laryngopharyngeal reflux (LPR), which can affect anyone. Adults
with LPR often complain that the back of their throat has a bitter
taste, a sensation of burning, or something “stuck.” Some may
have difficulty breathing if the voice box is affected.
In infants and children,
LPR may cause breathing problems such as: cough, hoarseness, stridor
(noisy breathing), croup, asthma, sleep disordered breathing,
feeding difficulty (spitting up), turning blue (cyanosis), aspiration,
pauses in breathing (apnea), apparent life threatening event (ALTE),
and even a severe deficiency in growth. Proper treatment of LPR,
especially in children, is critical.
What are the
symptoms of GERD and LPR?
The symptoms of GERD
may include persistent heartburn, acid regurgitation, nausea,
hoarseness in the morning, or trouble swallowing. Some people
have GERD without heartburn. Instead, they experience pain in
the chest that can be severe enough to mimic the pain of a heart
attack. GERD can also cause a dry cough and bad breath. Some people
with LPR may feel as if they have food stuck in their throat,
a bitter taste in the mouth on waking, or difficulty breathing
although uncommon.
If you experience any symptoms
on a regular basis (twice a week or more) then you may have GERD
or LPR. For proper diagnosis and treatment, you should be evaluated
by your primary care doctor for GERD or an otolaryngologist—head
and neck surgeon (ENT doctor).
Who gets GERD
or LPR?
Women, men, infants,
and children can all have GERD. This disorder may result from
physical causes or lifestyle factors. Physical causes can include
a malfunctioning or abnormal lower esophageal sphincter muscle
(LES), hiatal hernia, abnormal esophageal contractions, and slow
emptying of the stomach. Lifestyle factors include diet (chocolate,
citrus, fatty foods, spices), destructive habits (overeating,
alcohol and tobacco abuse) and even pregnancy. Young children
experience GERD and LPR due to the developmental immaturity of
both the upper and lower esophageal sphincters.
Unfortunately, GERD
and LPR are often overlooked in infants and children leading to
repeated vomiting, coughing in GER and airway and respiratory
problems in LPR such as sore throat and ear infections. Most infants
grow out of GERD or LPR by the end of their first year; however,
the problems that resulted from the GERD or LPR may persist.
What role does
an ear, nose, and throat specialist have in treating GERD and
LPR?
A gastroenterologist,
a specialist in treating gastrointestinal orders, will often provide
initial treatment for GERD. But there are ear, nose, and throat
problems that are either caused by or associated with GERD, such
as hoarseness, laryngeal (singers) nodules, croup, airway stenosis
(narrowing), swallowing difficulties, throat pain, and sinus infections.
These problems require an otolaryngologist—head and neck surgeon,
or a specialist who has extensive experience with the tools that
diagnose GERD and LPR. They treat many of the complications of
GERD, including: sinus and ear infections, throat and laryngeal
inflammation and lesions, as well as a change in the esophageal
lining called Barrett’s esophagus, which is a serious complication
that can lead to cancer.
Your primary care physician
or pediatrician will often refer a case of LPR to an ear nose
throat surgeon for evaluation, diagnosis, and treatment.
Diagnosing
and treating GERD and LPR
In adults, GERD can
be diagnosed or evaluated by a physical examination and the patient’s
response to a trial of treatment with medication. Other tests
that may be needed include an endoscopic examination (a long tube
with a camera inserted into the nose, throat, windpipe, or esophagus),
biopsy, x-ray, examination of the throat and larynx, 24 hour pH
probe, acid reflux testing, esophageal motility testing (manometry),
emptying studies of the stomach, and esophageal acid perfusion
(Bernstein test). Endoscopic examination, biopsy, and x-ray may
be performed as an outpatient or in a hospital setting. Endoscopic
examinations can often be performed in your ENT’s office, or may
require some form of sedation and occasionally anesthesia.
Symptoms of GERD or
LPR in children should be discussed with your pediatrician for
a possible referral to a specialist.
Most people with GERD
respond favorably to a combination of lifestyle changes and medication.
On occasion, surgery is recommended. Medications that could be
prescribed include antacids, histamine antagonists, proton pump
inhibitors, pro-motility drugs, and foam barrier medications.
Some of these products are now available over-the-counter and
do not require a prescription.
Children and adults
who fail medical treatment or have anatomical abnormalities
may require surgical intervention. Such treatment includes fundoplication,
a procedure where a part of the stomach is wrapped around the
lower esophagus to tighten the LES, and endoscopy, where hand
stitches or a laser is used to make the LES tighter.
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Adult
lifestyle changes to prevent GERD and LPR |
- Avoid eating and drinking
within two to three hours prior to bedtime
- Do not drink alcohol
- Eat small meals and slowly
- Limit problem foods:
- Caffeine
- Carbonated drinks
- Chocolate
- Peppermint
- Tomato and citrus foods
- Fatty and fried foods
- Lose weight
- Quit smoking
- Wear loose clothing
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